I think now at the radiocarbon dating;which revolutionized arheologia. radiocarbon .Dating was made by Willard Frank Libby
1960.Recently in the year -2010, researchers-Andre Geinand and Konstantin Novoselov of University Manchester have developed important work on graphene and in the 2011 were on important works, discoveries sensational on (fullerenes) so I wish to emphasize the importance of scientific research perspectives
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Andre Gein |
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Manchester |
Graphen |
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Konstantin Novoselov |
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University |
Manchester |
Graphen |
I think the analysis of molecular spectroscopic
determining the structure of diatomic including free radicals
This method including being able to help an astronomical object--- Work conducted by Gerhard Herzberg
I think and’’ mass spectrometry’’-RMN Macromolecular biological analysis.Very important analysis ‚’’ionization electrosparay’’ who in 2002 helped to produce many medicines
recently researchers
University Purdue by US
Eilchi Negischi
Richard Neck of University Delaware
Akira Suzuki of University Hokaido have done tremendous research
in the field of organic synthesis.
I mention that and also make a parallel between astronomical objects research.,realised by Gerhard Herzberg and
mass spectrometry ,
RMN- Molecular biological analysis-- ionization electrosparay’’ plus the fact that in the year 2009 discovered how chromosomes are protected by telomeres and the enzyme telomerase
Blackburn,Szotak,Greiden
as a research report scientific that I sent to universities I developed the hypothesis scientifically as the study of amino acid type B from certain plant species, such’’Chelidonium Majus’’,..’’Veratrum Album’’ and experiments on the gene, genetic recombination .The use of superior forms of chromosomes to improve plant species’’Chelidonium,.+Veratrum’’ containing substances with anticancer properties by .
By protoplast fusion, hybridization obtain a hybrid from two species of plants of the same biological family. example in 1970 was obtained hybrid tomato-potato In a previous comment I posted on facebook stressed the importance of enzymes in protein synthesis .
Finally I wish to emphasize the existence of huge importance possibility of making TRANSFORM an essential amino acid, amino acids existing in proteins animals.by physico-chemical methods, nuclear physics methodes I’m back to the importance of the contact - COOH,, ,,,,,NH2 and the real possibility of dissolution it
a normal amino acid, which inhibits the uncontrolled multiplication of cancer cells
Especialy ------I formulate a comment thinking at ‚’’Vladimir Prelog’’which was a Bosnian Croat chemist
Importance of his works is known about the stereochemistry of enzyme-catalysis reactions
I begin by expressing my my point of view by emphasizing importance Teoriei structure of organic compounds AM Butelerov . and recall that chemical properties of chemical combinations are reflected in the configuration (spatial structures) of these molecules
The chemistry which studying the how settlement of atoms in space called stereochemistry
As in my profile on Facebook i shown, at’’’ the interest’’’that i’m interested in scientific research projects .
So specified ‚’’Ilmari Virtanen’’’ has made several discoveries in nutrition and agricultural chemistry ,particularly interesting is ‚’’his discovery -1924’’’ on the phosphorylation hexoses and demonstrated that phosphorylation is the first step in the fermentation. He also produced works on nitrogen fixing bacteria, improved methods of conservation feed (AIV) . method was invented in 1932 to practice a kind of storage, plus hydrochloric acid or sulfuric acid, which stops harmful fermentation and does not harm animals.
He also helped develop methods of use and ammonium salts and urea in feed for the animals substituting vegetable protein - such as soy flour bones . Also’’James Batchellor’’ was the first American biochemist seek promotion crystallized an enzyme (urease), later crystallized an enzyme (catalase )and worked purification for other enzymes. through his work demonstrated that enzymes are in majority –proteins-- in fact he became director of the laboratory ‚’Cornell Enzime’’
In 1947 Carl Ferdinand Cori si Gerty Cory discovered the mechanism of glycogen biosynthesis, and recently in 2010’’ Robert G Edward’’ has made contributions to the development ‚’’fertilization in vitro ‚’’ i was made this listing of this research, because I believe that the results of these findings can fully solve the problem of cure leukemia.
So consider that plasma proteins - albumin, fibrinogen, globulins are of great importance to study the mechanism forcing the Further research deepening of their biosynthesis.
Is urgently necessary studying, researching regulatory proteins involved in controlling protein synthesis in cells ----ARN polymerase, including trascript leader--- including at least two amino acids in tandem ,(specifically ..........--- COOH and NH2 joining two amino acids in tandem)
In a research project I conducted a few years ago, I developed a hypothesis regarding the’’’ G protein’’’ - in order to clarify and more accurate understanding of its.
Begining from the mechanism of (cholera toxin action), the final conclusion that i had reached a point is that GTP isnot hydrolyzed by GDP for the proper functioning of ‚’’protein G ‚’’ for clarification and more precise understanding of its.
This is not a revelation, but an exact formulation that can help scientific research easier to understand mechanism of action of these is proteins for explained at all peoples
In 1946 John Howard Northrop conducted the study of enzymes essential for digestion and crystallized pepsin, trypsin, chymotrypsin. Merredith Wendell Stanley, biochemist American Merredith Wendell Stanley, biochemist American crystallized tobacco mosaic virus and helped develop a vaccine against flu .
In 1947 Sir Robert Robinson English chemist has developed studies of colored substances in plants (anthocyanins and alkaloids).
In 1948 Swedish biochemist performed protein electrophoresis technique used to analyze and separate colloids based on electrically charged colloidal particles move in electric field. In 1955 Hugo Theorell He also invented the mode of action of oxidative enzymes
In 1970 Werner Albert, Daniel Nathans, Hamilton O Smith (Sweden) found restriction enzymes and their application in molecular genetics.
In 1999 Fischer and Edwin G Krebs Edmond.H found that reversible phosphorylation is a biological mechanism is aproteinelor regulatory
My opinion is that problem complete healing of the leukemia is plasma protein-protein that make up blood plasma - albumin, globulins, fibrinogen This requires the discovery of the mechanism of their biosynthesis and specifically the study of regulatory proteins that control protein synthesis range in ARN polymerase from cells including the leader transcript including at least two amino acids connected in tandem exactly --- --- COOH carboxyl and amino (NH2) with the elimination of water molecules
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Sir Robert Robinson
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was an English chemist who made important studies on a colored substances from plants(anthocyanins and alcaloits)
beladonici alkaloids are plants activity for disease
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beladonici alkaloids are – ‚’’atropine, hyoscyamine, scopolamine- ‚’’
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Atroppa Belladona,Datura Stramonium |
anticholinergic alkaloids
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opium alkaloids type |
Papaver Somniferum |
analgesics |
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Reserpina |
Rauwolfia Serpentina |
antihypertensive, psychotropic |
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SHAPE \* MERGEFORMAT |
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Anthocyanins are naturally occurring glycosides in plants consist of six compo
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malvidina |
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petanidina |
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peonidina |
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delfinidina |
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cianidine |
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pelargenidine |
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· phisostygmina |
· Phisostigmina venosum |
· colinergic |
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· colchicine |
· Colchicum autumnale |
· Gout |
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· tubocurarine |
· Strychnos Sp,Chondodendron tomentosum |
· muscle relaxant |
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· vincristine, vinblastine |
· Caltharantus Roseus |
· anti-cancer |
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· Quinine, quinidine |
· Chinchona Sp |
· antimalarial, anti-arrhythmic heart |
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codeine, morphine |
Papaver Somniferum |
analgesic |
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phisostygmina |
Phisostigmina venosum |
colinergic |
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colchicine |
Colchicum autumnale |
Gout |
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tubocurarine |
Strychnos Sp,Chondodendron tomentosum |
muscle relaxant |
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vincristine, vinblastine |
Caltharantus Roseus |
anti-cancer |
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Quinine, quinidine |
Chinchona Sp |
antimalarial, anti-arrhythmic heart |
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codeine, morphine |
Papaver Somniferum |
analgesic |
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phisostygmina |
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colchicine |
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vincristine, vinblastine |
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Concerning ---Microbiological methods, biochemical, chemical for studying |
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Anthocyanins, |
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In this enzyme there is a transformation of anthocyanins. Organic acids miners have cytolytic action
My personal opinion is about what I posted in my facebook profile in the’’’ field of interest’’,and now i repeat (the role played by the great scientist Gabriel Bertrand and communist censorship) of university courses and textbooks in Romania
Concerning--- anthocyanins in press solubility in organic solvents, mention use organic solvents as benzene, aliphatic hydrocarbons etiacetatul, petroleum ether, diethyl ether
My personal opinion is about what I posted in my facebook profile in the’’’ field of interest’’,and now i repeat (the role played by the great scientist ‚’’ Herman Kolbe’’ who discovered paraffinic hydrocarbons and communist censorship of university courses and textbooks in Romania.
Also mention Pierre Bertholet and Hydrocarbon synthesis ,and communist censhorship of university courses and textbooks in Romania.
to obtain preparations anthocyanins using precipitation with lead salts
acid precipitation, thin layer chromatography and paper, mass spectroscopy, vibration spectroscopy(IR)
On antitumor properties of anthocyanins
Blocking cycle phases celelar [G1/ GO, G2/M’’) In less than 10% as normall cells
Human intestinal cancer cells HT-29, beneficially presents service-tree plants, blueberries, grapes.
Hydroxylated derivatives of 7-hydroxy salt 2 fenilbenzenpiriliu Found in plants in the free state called antocianide or as glycosides.
DELFINIDINE.
THIS anthocyanin color variation dependent of the medium pH-
cianidina anthocyanins gives colour of ---------- red rose luteolin anthocyanins give a yellow colour by ---chamomile
quercitina anthocyanins give a yellow colour of violet
catechins (hidroderivat of flavanului) is colorless
catechin tannins found in spruce, oak, chestnut, birch anthocyanins are the most polarizing substances of natural phenolic compounds all groups
.For understanding the importance of alkaloids, anthocyanins present in plants must be urgently directed fraud due to censorship of textbooks and university courses fraud due to censorship I say this because these are the basics, the ABC that starts and without which a student to break the career future unable to understand what is complicated notions recent innovations in science.
This does not mean that education and research in Romania has no value and that has stalled Some students, teachers understood the insidious way in which censorship was using and through self-study, self-improvement led on Romanian education fame abroad cocursurile won numerous awards in international gold, silver, bronze
but unfortunately for most 98% of students find it impossible to understand the latest issues of science, technology advances, their professional careers are destroyed
In Romania after a graduating faculty in 90% of students abandon the profession for which they trained, lack of jobs, but also because of poor professional training acquired in Faculty
Sir Robert Robinson
was an English chemist who made important studies on aa colored substances from plants(anthocyanins and alcaloits) beladonici alkaloids are plants activity for disease
Anthocyanins are naturally occurring glycosides in plants consist of six compo
Microbiological methods, biochemical, chemical for studying anthocyanins
Sir Robert Robinson
was an English chemist who made important studies on aa colored substances from plants(anthocyanins and alcaloits) beladonici alkaloids are plants activity for disease
Anthocyanins are naturally occurring glycosides in plants consist of six compo
Microbiological methods, biochemical, chemical for studying anthocyanins
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Microbiological methods, biochemical, chemical for studying anthocyanins
Albert Szent Gyorgy
revealed mechanism oxidation and decomposition processes of vitamin C. As is known ascorbic acid is very important L-enantiomer acid also called vitamin C ascorbicse. ascorbic acid is used as a food additive Peoples have lost capacity to synthesize ascorbic acid .Walter Haworth determined the structure of ascorbic acid.
Name of the relevant European food additives are:E300 ascorbic acid,E302 calcium ascorbat
E303 ascorbat potassium,E303-- ascorbic acid ester. Ascorbic acid meets in fruits and vegetables. Use of ascorbic acid preventing the degradation of fats by autooxidation (Rancidity aldehyde). Fats oxidative degraded have harmful effects on the body destroy vitamins A, E, C, B6 (beriberi) In plants L-ascorbic acid is essential for photosynthetic activity by transformation of superoxide and hydrogen peroxide in chloroplasts in the absence of catalase. Ascorbic acid is involved in regeneration of alpha-tocopherol. Vitamin C, plays an important role in tissue protection. Specifically, ascorbic acid helps the body to fight foreign invaders and tumor cells, supporting the cardiovascular system and assists the nervous system. Amino acids by making certain transformations determined amino acids transformed in in certain neurotransmittersAscorbic acid contribute to a variety of biochemical functions, biosynthesis of amino acids and amines. On ascorbic acid extraction method is to note the importance of secondary processes, one that refers to acid 2 / / cetogluconic (particulary). Acid metaphosphoric inhibit oxidation L-ascorbic acid, inhibit the metal catalyst and precipitate proteins. Many plants contain ascorbic acid oxidase, which catalyzes the oxidation of ascorbic acid to dehydroascorbic acid.
Ascorbic acid / ---- --- ascorbate---- dehydroascorbic acid.
For the determination of ascorbic acid, mention of, again and again chromatography role (HPPL) and to specify the following on the method of titration 26 --- Diclorindophenol. I will refer to the reduction of DCIP not limited to L-ascorbic acid and any substance present in the sample, which can reduce the dye. Thus the interference can lead to erroneous measurements if not recognized substances can interfere heated iron ions, tin ions, sulfite, thiosulfate, betaine, cysteine, glutathione.
Posibility for transform certain amino acids is a fact that is based on biochemical properties of amino acid bio properties. Through decarboxylation when heated inert solvent, ornithine turns putresceinne. Treatment with bases to form salts ,at treatment with ammonia forming amides, histidine – histamine.
By valine alkylation reaction is converted into N = metilvalina,glicol—betaina,
On reaction with nitrous acid (reaction Van Slike),the aspartic acid----------malic acid. Aldehyde reaction with leads to Schiff bases:alpha alanina----
Albert Szent Gyorgy
revealed mechanism oxidation and decomposition processes of vitamin C. As is known ascorbic acid is very important L-enantiomer acid also called vitamin C ascorbicse. ascorbic acid is used as a food additive Peoples have lost capacity to synthesize ascorbic acid .Walter Haworth determined the structure of ascorbic acid.
Name of the relevant European food additives are:E300 ascorbic acid,E302 calcium ascorbat
E303 ascorbat potassium,E303-- ascorbic acid ester. Ascorbic acid meets in fruits and vegetables. Use of ascorbic acid preventing the degradation of fats by autooxidation (Rancidity aldehyde). Fats oxidative degraded have harmful effects on the body destroy vitamins A, E, C, B6 (beriberi) In plants L-ascorbic acid is essential for photosynthetic activity by transformation of superoxide and hydrogen peroxide in chloroplasts in the absence of catalase. Ascorbic acid is involved in regeneration of alpha-tocopherol. Vitamin C, plays an important role in tissue protection. Specifically, ascorbic acid helps the body to fight foreign invaders and tumor cells, supporting the cardiovascular system and assists the nervous system. Amino acids by making certain transformations determined amino acids transformed in in certain neurotransmittersAscorbic acid contribute to a variety of biochemical functions, biosynthesis of amino acids and amines. On ascorbic acid extraction method is to note the importance of secondary processes, one that refers to acid 2 / / cetogluconic (particulary). Acid metaphosphoric inhibit oxidation L-ascorbic acid, inhibit the metal catalyst and precipitate proteins. Many plants contain ascorbic acid oxidase, which catalyzes the oxidation of ascorbic acid to dehydroascorbic acid.
Ascorbic acid / ---- --- ascorbate---- dehydroascorbic acid.
For the determination of ascorbic acid, mention of, again and again chromatography role (HPPL) and to specify the following on the method of titration 26 --- Diclorindophenol. I will refer to the reduction of DCIP not limited to L-ascorbic acid and any substance present in the sample, which can reduce the dye. Thus the interference can lead to erroneous measurements if not recognized substances can interfere heated iron ions, tin ions, sulfite, thiosulfate, betaine, cysteine, glutathione.
By valine alkylation reaction is converted into N = metilvalina,glicol—betaina,
On reaction with nitrous acid (reaction Van Slike),the aspartic acid----------malic acid. Aldehyde reaction with leads to Schiff bases:alpha alanina----
metilalanina
Alpha amino acids with transition metal ions form colored compounds alpha amino acids, soluble chelate heavy set(from what I thought the Grignard reaction in my research essay) on the posibility to obtain, discover new vitamins based on the principle of transformation sterols (phytosterols from soy). In this emphasiz method used by Adolph ‚’’ Otto Reinhold
Windhaus’’---)dehydrocholesterol and vitamin D3:Also i mention that Alfred Werner inorganic pharmacy had obtained the hexolle. Be noted that deamination of amino acids, alpha-alanine by using aminoacidooxidaza is obtained pyruvic acid.
By deamination Desaturate (alpha alanine) resulting acrylic acid..
Using hydrolysates amino acid (alpha alaniana) is transformed into lactic acid. By decarboxylation of Alpha alanine to obtain etilaneina:HISTIDINA------hystamine
On glicocol - betaine, glicocolul emphasize stahidrina wich was isolated from plant Gladiolus
I especialy mention that
macropeptidele contain more than 100 amino acids, peptides BOND. A very important peptide is L-aspartyl-B-phenyl-L-alanimetile glutathione ester, which acts as a coenzyme. Researchs for macropeptides is an excellent source of amino acids and separation. Emphasize that on transaminare
glutamic acid + pyruvic acid ------------result ---- alpha cetoglutanic acid + alpha alanine
Glicocolic acid derivatives are glycol and acid hiparic, sarconina, N-methyl glicoco